NATURAL SCIENCES

Journal of fundamental
and
applied researches

Adaptive capacity of bodies of immune system of rats in the conditions of the stress

2014. №4, pp. 67-71

Roskova Irina S. - Ph.D. (Medicine), Associate Professor, Astrakhan State Medical University, 121 Bakinskaya Str., Astrakhan, 414000, Russian Federation, polyris@list.ru

Teply David L. - D.Sc. (Biology), Professor, Head of Chair, Astrakhan State University, 1 Shaumyan Sq., Astrakhan, 414000, Russian Federation, dima.tepliy@yandex.ru

The condition of free radical processes in bodies of immune system at white rats - males in post-natal ontogenesis in the conditions of chronic intoxication is studied. Age features of speed of lipid peroxidation in thymus gland, lymph nodes and a spleen of rats are opened in normal and at chronic influence of sour natural gas of the Astrakhan gas-condensate field. Comparison of dynamics of level of free radical processes in tissue homogenates immune system of rats at various stages of ontogenesis is carried out at chronic influence of sour natural gas. It is established that the obtained experimental data testify to decrease in stability of thymus gland, lymph nodes and a spleen of rats with age and to exhaustion of antioxidant system.

Key words: интоксикация, свободнорадикальные процессы, иммунная система, тимус, лимфатические узлы, селезенка, перекисное окисление липидов, intoxication, free radical processes, immunal system, thymus gland, lymph nodes, spleen, lipid peroxidation