NATURAL SCIENCES

Journal of fundamental
and
applied researches

THE SORPTION OF PROCAINAMIDE BY CARBON-MINERAL SORBENT OBTAINED FROM PHRAGMITES AUSTRALIS

2017. №2, pp. 89-97

Zolotareva Natalia V. - Ph.D. (Engineering), Associate Professor, Astrakhan State University, 20a Tatishcheva Str., Astrakhan, 414000, Russian Federation, zoloto.chem@mail.ru

Alykova Tamara V. - Ph.D. (Chemistry), Professor, Astrakhan State University, 20a Tatishcheva Str., Astrakhan, 414000, Russian Federation, t.alykova@mail.ru

Evsina Elena M. - Ph.D. (Engineering), Associate Professor, Astrakhan State University, 20a Tatishcheva Str., Astrakhan, 414000, Russian Federation, evsinalena@mail.ru

Boyko Vadim A. - Master of Science, Astrakhan State University, 20a Tatishcheva Str., Astrakhan, 414000, Russian Federation, alfa_vadim@mail.ru

Kudryashova Anastasia Ye. - student, Astrakhan State University, 20a Tatishcheva Str., Astrakhan, 414000, Russian Federation, acyaalykova@mail.ru

The adsorption of the antiarrhythmic drug procainamide on carbon-mineral sorbent obtained from the natural material of phragmites australis is studied in this research paper. It has been ascertained from experimental data that adsorption occurs most efficiently at pH 2 and increases with the increasing of temperature. Sorptive capacity of the sorbent is 20 mg/m. We used experimentally obtained results of thermodynamic characteristics of procainamide adsorption on the carbon-mineral sorbent and quantum-chemical calculation methods to model the process of adsorption and to study its mechanism. Our researches showed that the energy characteristics of adsorption of procainamide on the sorbent are close to values obtained on the basis of quantum-chemical calculations using the cluster approach. It follows from the calculations that the configuration of the coal cluster in modeling the adsorption of procainamide on the sorbent is not decisive. The energy of adsorption depends on the presence of hydroxyl groups on the surface and the presence of adsorbed molecules. The high adsorption properties of the sorbent towards procainamide can be used in enterosorption for removing this type of medications from different media.

Key words: угольно-минеральный сорбент, новокаинамид, адсорбция, модели активного угля, конфигурация кластеров, carbon-mineral sorbent, procainamide, adsorption, models of active carbon, configuration of clusters