NATURAL SCIENCES

Journal of fundamental
and
applied researches

The risc factors of ischemic heart disease and arterial hypertension in patients with bronchial asthma

2014. 4, pp. 28-34

Akhmineeva Aziza Kh. - Ph.D. (Medicine), Associate Professor, Astrakhan State Medical University, 121 Bakinskaya Str., Astrakhan, 414000, Russian Federation, aaziza@mail.ru

Polunina Olga S. - D.Sc. (Medicine), Professor, Head of Chair, Astrakhan State Medical University, 121 Bakinskaya Str., Astrakhan, 414000, Russian Federation, admed@yandex.ru

Sevostyanova Irina V. - Ph.D. (Medicine), Assistant, Astrakhan State Medical University, 121 Bakinskaya Str., Astrakhan, 414000, Russian Federation, irina-nurzhanova@yandex.ru

For prognosis the development of arterial hypertension and ischemic heart disease in patients with bronchial asthma (BA) we have carried out in-depth analysis of a number of clinical and laboratory parameters (gender-age characteristics, length and severity of BA, the state of the vascular endothelium, polymorphism of endothelial nitric oxide synthase gene, inflammatory activity and the level of oxidative stress) and we have also worked out prognostic algorithms of development of arterial hypertension and ischemic heart disease at BA. These algorithms allow making the prognosis of development of arterial hypertension and ischemic heart disease in BA patients, which permits early diagnosis of respiratory cardiac comorbidity, allows selecting the groups of BA patients with a high risk of arterial hypertension and ischemic heart disease and carrying out integrated preventive measures in these groups.

Key words: , , , , , , , , , , bronchial asthma, ischemic heart disease, arte

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